分子量:47.6 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Rat LAG3, His Tag by the LAL method.

Buffer:PBS, pH7.4

生物活性:

产品特性:Rat LAG3, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 47.6 kDa. The predicted N-terminus is Gly 24. The reducing (R) protein migrates as 55 kDa in SDS-PAGE  due to glycosylation.

产品背景:Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.