FITC标记的胞浆蛋白PACSIN3抗体
产品名称： FITC标记的胞浆蛋白PACSIN3抗体
英文名称： Anti-PACSIN3/FITC
产品编号： HZ-13659R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PACSIN3/FITC Conjugated antibody
FITC标记的胞浆蛋白PACSIN3抗体
| 英文名称 | Anti-PACSIN3/FITC |
| 中文名称 | FITC标记的胞浆蛋白PACSIN3抗体 |
| 别 名 | Endophilin 1; Endophilin I; FLJ17861; OTTHUMP00000234262; OTTHUMP00000234263; OTTHUMP00000234264; PACN3_HUMAN; Pacsin3; Protein kinase C and casein kinase substrate in neurons 3; Protein kinase C and casein kinase substrate in neurons protein 3; SDPIII; SH3 domain containing protein 6511; SH3 domain-containing protein 6511; syndapin III; |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 48kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PACSIN3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity). Function: May play a role in vesicle formation and transport. Subcellular Location: Cytoplasm. Cell membrane. Detected at the inner aspect of the plasma membrane in cells or myotubes. Tissue Specificity: Expressed in heart and skeletal muscle, lung, kidney, adrenal gland and placenta. Post-translational modifications: Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). Similarity: Belongs to the PACSIN family. Contains 1 FCH domain. Contains 1 SH3 domain. Database links: Entrez Gene: 29763 Human Entrez Gene: 80708 Mouse Omim: 606513 Human SwissProt: Q9UKS6 Human SwissProt: Q99JB8 Mouse Unigene: 334639 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
在胞吞作用中起调节内膜蛋白内化的作用。过表达抑制SLC2A1/GLUT1和TRPV4的内化，增加细胞膜上SLC2A1/GLUT1和TRPV4的水平。抑制TrPV4钙通道活性（通过相似性）。