FITC标记的酮基移换酶样蛋白1抗体
产品名称： FITC标记的酮基移换酶样蛋白1抗体
英文名称： Anti-TKTL1/FITC
产品编号： HZ-6284R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-TKTL1/FITC Conjugated antibody
FITC标记的酮基移换酶样蛋白1抗体
| 英文名称 | Anti-TKTL1/FITC |
| 中文名称 | FITC标记的酮基移换酶样蛋白1抗体 |
| 别 名 | TK 2; TK2; TKR; TKT 2; TKT2; TKTL1; TKTL1_HUMAN; Transketolase 2; Transketolase like 1; Transketolase like protein 1; Transketolase related protein; Transketolase-like protein 1; Transketolase-related protein; Transketolase2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 信号转导 肿瘤细胞生物标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 65 kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TKTL1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. Function: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate Subunit: Homodimer Subcellular Location: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic and to a lesser extent also nuclear. Tissue Specificity: Expressed in fetal and adult heart, brain, lung, liver, and kidney, and in adult placenta, skeletal muscle and pancreas. Up-regulated in various epithelial tumors. Similarity: Belongs to the transketolase family. Database links: Entrez Gene: 8277 Human Omim: 300044 Human SwissProt: P51854 Human Unigene: 102866 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白是一种转酮醇酶，其充当同源二聚体，并催化七肽庚糖-7-磷酸和D-甘油醛3-磷酸转化为D-核糖5-磷酸和D-木酮糖5-磷酸。这种反应将戊糖磷酸途径与糖酵解途径联系起来。这种基因的变异可能是Wernicke Korsakoff综合征的原因。已经发现了三个编码不同亚型的转录本变体。