FITC标记的锌指蛋白136抗体
产品名称： FITC标记的锌指蛋白136抗体
英文名称： Anti-ZNF136/FITC
产品编号： HZ-18492R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ZNF136/FITC Conjugated antibody
FITC标记的锌指蛋白136抗体
| 英文名称 | Anti-ZNF136/FITC |
| 中文名称 | FITC标记的锌指蛋白136抗体 |
| 别 名 | pHZ 20; Zinc finger protein 136; Zinc finger protein 136 clone pHZ 20; ZN136_HUMAN; ZNF136. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 转录调节因子 锌指蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 63kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF136 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: ZNF136 is a transcriptional regulator belonging to the Krüppel C2H2-type zinc-finger protein family. It is a ubiquitously expressed protein, localizes to the nucleus and contains 14 C2H2-type zinc fingers and 1 KRAB A-domain. Alone, ZNF136 functions as a weak repressor; however, when fused with a heterologous KRAB B-domain containing protein, such as ZNF10, ZNF136 functions as a potent repressor. Function: May be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain. Subcellular Location: Nucleus. Tissue Specificity: Seems ubiquitous. Seen in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 14 C2H2-type zinc fingers. Contains 1 KRAB domain. Database links: Entrez Gene: 7695 Human Omim: 604078 Human SwissProt: P52737 Human Unigene: 479874 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
ZNF136是属于Kr upp-C2H2型锌指蛋白家族的转录调节子。它是一个广泛表达的蛋白，定位于细胞核，含有14个C2H2型锌指和1个KrAb A结构域。单独使用时，ZNF136起弱抑制剂的作用；然而，当与含有异源KRAB结构域的蛋白质（如ZNF10）融合时，ZNF136起强抑制剂的作用。