FITC标记的PROSC蛋白抗体
产品名称： FITC标记的PROSC蛋白抗体
英文名称： Anti-PROSC/FITC
产品编号： HZ-19184R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PROSC/FITC Conjugated antibody
FITC标记的PROSC蛋白抗体
| 英文名称 | Anti-PROSC/FITC |
| 中文名称 | FITC标记的PROSC蛋白抗体 |
| 别 名 | FLJ11861; Proline synthase co-transcribed bacterial homolog protein; Proline synthetase co transcribed bacterial homolog; Proline synthetase co transcribed homolog (bacterial); PROSC; PROSC_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 泛素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 30kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PROSC |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: PROSC is a 275 amino acid ubiquitously expressed enzyme that is highly conserved from bacteria to mammals. The gene encoding PROSC is cotranscribed with proline sythetase. PROSC requires the cofactor pyridoxal phosphate, the active form of vitamin B6 that acts in all transamination reactions. The PROSC gene maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. Tissue Specificity: Ubiquitous. Similarity: Belongs to the UPF0001 family. Database links: Entrez Gene: 11212 Human Entrez Gene: 114863 Mouse Entrez Gene: 306544 Rat Omim: 604436 Human SwissProt: O94903 Human SwissProt: Q9Z2Y8 Mouse Unigene: 304792 Human Unigene: 608177 Human Unigene: 277501 Mouse Unigene: 485663 Mouse Unigene: 228631 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
PROSC是一种由细菌到哺乳动物高度保守的275氨基酸的普遍表达的酶。脯氨酸合成酶基因与脯氨酸合成酶共转录。PROSC需要辅因子吡哆醛磷酸盐，它是在所有转氨基反应中起作用的维生素B6的活性形式。PROSC基因定位于人类染色体8，由近1亿4600万个碱基组成，编码约800个基因。在一些白血病和淋巴瘤中发现8号染色体部分移位，并伴有c-Myc基因的扩增，并且通常与较差的预后相关。8号染色体的部分与精神分裂症和双相情感障碍有关。第8号染色体也与菲佛综合征、先天性甲状腺功能减退症和Waord-Burg综合征有关。