Anti-GRIA4 Polyclonal Antibody
产品名称: Anti-GRIA4 Polyclonal Antibody
英文名称: GLUR4;GLURD;GluA4;GLUR4C
产品编号: K006773P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: IHC
北京索莱宝科技有限公司--实验室产品
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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.