[KO Validated] HuR/ELAVL1 Rabbit pAb (APR26267N)
产品名称: [KO Validated] HuR/ELAVL1 Rabbit pAb (APR26267N)
英文名称: [KO Validated] HuR/ELAVL1 Rabbit pAb (APR26267N)
产品编号: APR26267N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
分子量:Calculated MW: 36kDa/38kDa Observed MW: 36kDa 细胞定位:Cytoplasm, Nucleus 稀释方法:WB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:50 - 1:200 总结:The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.