[KO Validated] HuR/ELAVL1 Rabbit pAb (APR26267N)-抗体-抗体-生物在线
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[KO Validated] HuR/ELAVL1 Rabbit pAb (APR26267N)

[KO Validated] HuR/ELAVL1 Rabbit pAb (APR26267N)

商家询价

产品名称: [KO Validated] HuR/ELAVL1 Rabbit pAb (APR26267N)

英文名称: [KO Validated] HuR/ELAVL1 Rabbit pAb (APR26267N)

产品编号: APR26267N

产品价格: null

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围:

生物谷
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分子量:Calculated MW: 36kDa/38kDa
Observed MW: 36kDa

细胞定位:Cytoplasm, Nucleus

稀释方法:WB 1:500 - 1:1000
IHC 1:50 - 1:200
IF 1:50 - 1:200

总结:The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.