重组腺病毒早期E1A蛋白
英文名称 | Recombinant ADV 5 E1A protein, His |
中文名称 | 重组腺病毒早期E1A蛋白 |
别 名 | Adenovirus early E1A protein; Control protein E1A; E1A; Early E1A protein; Human adenovirus type 5; Human adenovirus C; pfam02703; E1A_ADE05; Recombinant ADV 5 E1A protein, His |
理论分子量 | 32kDa |
检测分子量 | 40 kDa |
性 状 | Lyophilized or Liquid |
浓 度 | >0.5 mg/ml |
物 种 | ADV |
序 列 | 1-289/289 |
纯 度 | >95% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | Not analyzed |
表达系统 | E.coli |
活性 | Not tested |
标签 | His |
缓 冲 液 | 20 mM Tris-HCl |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105. |
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